Measurement of humerus and radius bone mineral content in the term and preterm infant
We compared two anatomic sites for single-photon absorptiometric measurement of bone mineral content (BMC) in term and preterm infants. The distal one third of the radius and the midportion of the humerus were evaluated for measurements of BMC with an unmodified, commercially available bone densitometer. We assessed reproducibility of BMC and bone width (BW) measurements and defined normal at-birth ranges of BMC, BW, and BMC/BW ratio for infants with gestational ages of 24 to 42 weeks. Humerus BMC correlated with gestational age, birth weight, and BW of patients and did not differ from humerus BMC values determined over the same range of gestational ages at another center. Representative serial measurements of two very low birth weight (VLBW) infants are presented to demonstrate the feasibility of using humerus BMC in longitudinal studies to assess changes in bone mineralization. We conclude that bone densitometer measurements of mid-humerus BMC can be successfully performed and are preferable to similar measurements of the radius for VLBW infants. Normal humerus BMC values were defined for use in diagnosis and evaluation of the efficacy of treatment in VLBW infants who are at high risk of developing osteopenia of prematurity.
- Research Organization:
- Loma Linda Univ. Medical Center, CA (USA)
- OSTI ID:
- 6827902
- Journal Information:
- J. Pediatr.; (United States), Journal Name: J. Pediatr.; (United States) Vol. 113; ISSN JOPDA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
AGE GROUPS
BODY
CHILDREN
COMPUTERIZED TOMOGRAPHY
DENSITY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
EMISSION COMPUTED TOMOGRAPHY
INFANTS
MEASURING METHODS
MINERALIZATION
MINERALS
ORGANS
PHYSICAL PROPERTIES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
SKELETAL DISEASES
SKELETON
TOMOGRAPHY