Acute effects of ambient ozone on pulmonary function of children in The Netherlands
- Univ. of Wageningen (Netherlands)
In the spring and summer of 1989 an epidemiologic study was conducted to evaluate the acute effects of photochemical air pollution episodes on pulmonary function of children living in three nonindustrial towns in the Netherlands. Spirometry was performed repeatedly in the schools of the children, mostly during the morning hours. Data from 533 children having more than four valid pulmonary function tests were included in the analyses. The association between previous-day ambient ozone concentration and pulmonary function was evaluated, using individual linear regression analysis and subsequent evaluation of the distribution of individual regression coefficients. One hour maximum ambient ozone concentrations frequently exceeded 160 micrograms/m3 but were all lower than the Dutch Air Quality Guideline of 240 micrograms/m3 for all three populations. Significant negative associations of previous-day ambient ozone with FVC, FEV1, peak expiratory flow (PEF), and maximal midexpiratory flow (MMEF) were observed. There were indications of systematic differences in responses among the children. Children with chronic respiratory symptoms did not have a stronger response than children without these symptoms.
- OSTI ID:
- 6812965
- Journal Information:
- American Review of Respiratory Disease; (United States), Vol. 147:1; ISSN 0003-0805
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
CHILDREN
ENVIRONMENTAL EXPOSURE
RESPIRATION
PHOTOCHEMICAL OXIDANTS
BIOLOGICAL EFFECTS
FLOW RATE
VOLUME
AIR POLLUTION
AIR QUALITY
DYNAMIC FUNCTION STUDIES
NETHERLANDS
OZONE
REGRESSION ANALYSIS
AGE GROUPS
DEVELOPED COUNTRIES
ENVIRONMENTAL QUALITY
EUROPE
MATHEMATICS
POLLUTION
STATISTICS
560300* - Chemicals Metabolism & Toxicology