Acute effects of ambient ozone on pulmonary function of children in The Netherlands

Journal Article · Fri Jan 01 04:00:00 EST 1993 · American Review of Respiratory Disease; (United States)

DOI:https://doi.org/10.1164/ajrccm/147.1.111· OSTI ID:6812965

Hoek, G; Fischer, P; Brunekreef, B; Lebret, E; Hofschreuder, P; Mennen, M G ^[1]

---

1. Univ. of Wageningen (Netherlands)

In the spring and summer of 1989 an epidemiologic study was conducted to evaluate the acute effects of photochemical air pollution episodes on pulmonary function of children living in three nonindustrial towns in the Netherlands. Spirometry was performed repeatedly in the schools of the children, mostly during the morning hours. Data from 533 children having more than four valid pulmonary function tests were included in the analyses. The association between previous-day ambient ozone concentration and pulmonary function was evaluated, using individual linear regression analysis and subsequent evaluation of the distribution of individual regression coefficients. One hour maximum ambient ozone concentrations frequently exceeded 160 micrograms/m3 but were all lower than the Dutch Air Quality Guideline of 240 micrograms/m3 for all three populations. Significant negative associations of previous-day ambient ozone with FVC, FEV1, peak expiratory flow (PEF), and maximal midexpiratory flow (MMEF) were observed. There were indications of systematic differences in responses among the children. Children with chronic respiratory symptoms did not have a stronger response than children without these symptoms.

• OSTI ID: 6812965
• Journal Information: American Review of Respiratory Disease; (United States), Journal Name: American Review of Respiratory Disease; (United States) Vol. 147:1; ISSN ARDSBL; ISSN 0003-0805
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE GROUPS
AIR POLLUTION
AIR QUALITY
BIOLOGICAL EFFECTS
CHILDREN
DEVELOPED COUNTRIES
DYNAMIC FUNCTION STUDIES
ENVIRONMENTAL EXPOSURE
ENVIRONMENTAL QUALITY
EUROPE
FLOW RATE
MATHEMATICS
NETHERLANDS
OZONE
PHOTOCHEMICAL OXIDANTS
POLLUTION
REGRESSION ANALYSIS
RESPIRATION
STATISTICS
VOLUME