Effects of ambient ozone on respiratory function and symptoms in Mexico City schoolchildren

Journal Article · Sat Feb 01 04:00:00 EST 1992 · American Review of Respiratory Disease (New York); (United States)

DOI:https://doi.org/10.1164/ajrccm/145.2_Pt_1.276· OSTI ID:5747245

Castillejos, M; Gold, D R; Dockery, D; Tosteson, T; Baum, T; Speizer, F E ^[1]

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1. Universidad Autonoma Metropolitana-X, Mexico City, (Mexico)

The effects of ambient ozone (O3) on respiratory function and acute respiratory symptoms were evaluated in 143 7- to 9-yr-old schoolchildren followed longitudinally at 1- to 2-wk intervals over a period of 6 months at three schools in Pedregal, Mexico City. The maximum O3 level exceeded the World Health Organization guideline of 80 ppb and the U.S. standard of 120 ppb in every week. For an increase from lowest to highest in the mean O3 level during the 48 hr before spirometry (53 ppb), logistic regression estimated relative odds of 1.7 for a child reporting cough/phlegm on the day of spirometry. For the full population, the mean O3 level during the hour before spirometry, not adjusted for temperature and humidity, predicted a significant decrement in FVC but not in FEV1 or FEF25-75. In contrast, the mean O3 level during the previous 24-, 48-, and 168-h periods predicted significant decrements in FEV1 and FEF25-75 but not in FVC. Ozone was consistently associated with a greater decrement in lung function for the 15 children with chronic phlegm as compared with the children without chronic cough, chronic phlegm, or wheeze. Ozone in the previous 24-, 48-, and 168-h periods predicted decrements in FEV1 for children of mothers who were current or former smokers, but not for children of mothers who were never smokers. Many of these effects were reduced in multiple regression analyses including temperature and humidity, as temperature and O3 were highly correlated.

• OSTI ID: 5747245
• Journal Information: American Review of Respiratory Disease (New York); (United States), Journal Name: American Review of Respiratory Disease (New York); (United States) Vol. 145:2 Pt 1; ISSN ARDSB; ISSN 0003-0805
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
540120* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (1990-)
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE GROUPS
AIR POLLUTION
AIR POLLUTION MONITORING
CHILDREN
DEVELOPING COUNTRIES
DISEASES
ECOLOGICAL CONCENTRATION
LATIN AMERICA
MATHEMATICS
MEXICO
MONITORING
NORTH AMERICA
OZONE
POLLUTION
REGRESSION ANALYSIS
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
SENSITIVITY
STATISTICS
SYMPTOMS
TOXICITY