Effects of ambient ozone on respiratory function in active, normal children
Respiratory functions were measured on a daily basis by spirometry over a period of 4 wk at a summer camp at Fairview Lake in northwestern New Jersey. Fifty-three boys and 38 girls 8 to 15 yr of age participated in the study on at least 7 days; 37 children were in residence for 4 wk, 34 for the first 2 wk only; and 20 for the last 2 wk. There were 72 whites, 15 blacks, 3 Asians, and 1 Hispanic in the study group. Multiple regression analyses indicated that the O/sub 3/ concentration in the previous hour, the cumulative daily O/sub 3/ exposure during the hours between 9 A.M. and the function measurement, ambient temperature, and humidity were the most explanatory environmental variables for daily variations in function, with the 1 - h O/sub 3/ concentration having the strongest influence. Linear regressions were performed for each child between O/sub 3/ concentration and function, and all average slopes were significantly negative (p less than 0.05) for FVC, FEV1, PEFR, and FEF25-75 for all children, and for boys and girls separately. Comparable results were obtained in data subsets (i.e., children studied during the first or second 2 wk only, and for data sets truncated at O/sub 3/ less than 80 and O/sub 3/ less than 60 ppb). The average regression slopes (+/- SE) for FVC and FEV1, respectively, were -1.03 +/- 0.24 and -1.42 +/- 0.17 ml/ppb, whereas for PEFR and FEF25-75 they were -6.78 +/- 0.73 and -2.48 +/- 0.26 ml/s/ppb.
- Research Organization:
- New York Univ. Medical Center, Tuxedo (USA)
- OSTI ID:
- 5313638
- Journal Information:
- Am. Rev. Respir. Dis.; (United States), Vol. 137:2
- Country of Publication:
- United States
- Language:
- English
Similar Records
Effects of ambient ozone on respiratory function in active, normal children
Effects of ambient ozone on respiratory function in healthy adults exercising outdoors
Related Subjects
OZONE
BIOLOGICAL EFFECTS
RESPIRATORY SYSTEM
DYNAMIC FUNCTION STUDIES
CHILDREN
DAILY VARIATIONS
NEW JERSEY
REGRESSION ANALYSIS
RESPIRATION
AGE GROUPS
FEDERAL REGION II
MATHEMATICS
NORTH AMERICA
STATISTICS
USA
VARIATIONS
560300* - Chemicals Metabolism & Toxicology