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Effect of tsl (thermosensitive suppressor of lex) mutation on postreplication repair in Escherichia coli K-12. [Ultraviolet radiation]

Journal Article · · J. Bacteriol.; (United States)
OSTI ID:6801752

Cells of Escherichia coli K-12 carrying lexA or recA mutations are more sensitive to uv radiation than corresponding wild-type cells and are defective in postreplication repair. Suppressor mutations (tsl) have been described previously which increase the uv resistance of lexA uvr/sup +/, lexA uvrA, and recAl uvr/sup +/ strains, but not the resistance of recA1 uvrA strains. We have studied the effect of the tsl-1 mutation on postreplication repair and find that the enhanced survival conferred by this mutation is correlated with an increased capacity for postreplication repair.

Research Organization:
Stanford Univ., CA
OSTI ID:
6801752
Journal Information:
J. Bacteriol.; (United States), Journal Name: J. Bacteriol.; (United States) Vol. 135:3; ISSN JOBAA
Country of Publication:
United States
Language:
English