Graves' disease following irradiation for Hodgkin's disease

Journal Article · Fri Sep 22 04:00:00 EDT 1978 · J. Am. Med. Assoc.; (United States)

DOI:https://doi.org/10.1001/jama.240.13.1381· OSTI ID:6801449

Pilepich, M V; Jackson, I; Munzenrider, J E; Brown, R S

The thyroid gland is commonly included in the radiation field in patients with Hodgkin's disease treated with radiation therapy. The so-called mantle field routinely includes the neck. A substantial number of patients with non-Hodgkin's lymphoma, head and neck tumors, and breast carcinoma also receive neck irradiation. The thyroid was traditionally considered a radioresistant organ. However, several reports on thyroid dysfunction following neck irradiation have appeared in recent years. Although the exact incidence and pathogenesis are not known, hypothyroidism is a recognized complication of thyroid irradiation. Grave's disease following thyroid irradiation, manifested either as hyperthyroidism or ophthalmopathy, is not a well-recognized entity. A case is reported.

• Research Organization: Tufts-New England Medical Center, Boston
• OSTI ID: 6801449
• Journal Information: J. Am. Med. Assoc.; (United States), Journal Name: J. Am. Med. Assoc.; (United States) Vol. 240:13; ISSN JAMAA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CHEST
CHILDREN
DELAYED RADIATION EFFECTS
DISEASES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
GOITER
HODGKINS DISEASE
HYPERTHYROIDISM
IONIZING RADIATIONS
IRRADIATION
LOCAL IRRADIATION
LYMPHOMAS
MAMMALS
MAN
MEDICINE
NECK
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PRIMATES
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
THERAPY
THYROID
VERTEBRATES