Acute skin reactions in postoperative breast cancer patients receiving radiotherapy plus adjuvant chemotherapy
A group of 26 patients with operable carcinoma of the breast received postoperative radiotherapy plus adjuvant chemotherapy. Acute skin reactions were studied by clinical observation. There was a statistically significant difference (P less than .01) in the acute skin reactions in the chest wall area in those who received chemotherapy (81%) compared to the controls who received only radiotherapy (33%). Acute skin reactions began at the completion of postoperative radiotherapy and reached maximum severity 1 to 2 weeks later. They usually subsided after 4 to 6 weeks. No skin reactions were observed in the parasternal, supraclavicular fossa, or axillary regions. On the basis of these findings, postoperative radiotherapy combined with adjuvant chemotherapy is probably beneficial.
- Research Organization:
- Orebro Regional Hospital, Sweden
- OSTI ID:
- 6801307
- Journal Information:
- Am. J. Roentgenol.; (United States), Vol. 130:1
- Country of Publication:
- United States
- Language:
- English
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