Acute skin reactions in postoperative breast cancer patients receiving radiotherapy plus adjuvant chemotherapy

Journal Article · Sun Jan 01 04:00:00 EST 1978 · Am. J. Roentgenol.; (United States)

DOI:https://doi.org/10.2214/ajr.130.1.137· OSTI ID:6801307

Hahn, P; Hallberg, O; Vikterloef, K J

A group of 26 patients with operable carcinoma of the breast received postoperative radiotherapy plus adjuvant chemotherapy. Acute skin reactions were studied by clinical observation. There was a statistically significant difference (P less than .01) in the acute skin reactions in the chest wall area in those who received chemotherapy (81%) compared to the controls who received only radiotherapy (33%). Acute skin reactions began at the completion of postoperative radiotherapy and reached maximum severity 1 to 2 weeks later. They usually subsided after 4 to 6 weeks. No skin reactions were observed in the parasternal, supraclavicular fossa, or axillary regions. On the basis of these findings, postoperative radiotherapy combined with adjuvant chemotherapy is probably beneficial.

• Research Organization: Orebro Regional Hospital, Sweden
• OSTI ID: 6801307
• Journal Information: Am. J. Roentgenol.; (United States), Journal Name: Am. J. Roentgenol.; (United States) Vol. 130:1; ISSN AJROA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BODY
BODY AREAS
CARCINOMAS
CHEMOTHERAPY
CHEST
DAMAGE
DISEASES
ETIOLOGY
GLANDS
MAMMARY GLANDS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
RESPONSE MODIFYING FACTORS
SKIN
THERAPY