Differential diagnosis of solitary pulmonary nodules with positron emission tomography using (/sup 11/C)L-methionine

Journal Article · Thu Sep 01 00:00:00 EDT 1988 · J. Comput. Assist. Tomogr.; (United States)

DOI:https://doi.org/10.1097/00004728-198809010-00015· OSTI ID:6799460

Kubota, K; Matsuzawa, T; Fujiwara, T; Abe, Y; Ito, M; Hatazawa, J; Ido, T; Ishiwata, K; Watanuki, S

Two patients with solitary pulmonary nodules, 1.5-2.0 cm in diameter, were studied by positron emission tomography using (/sup 11/C-Methyl)L-methionine (/sup 11/C-Met). Case 1 showed high accumulation of /sup 11/C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with /sup 11/C-Met seems to be useful for the differential diagnosis of solitary lung nodules.

• Research Organization: Tohoku Univ., Sendai (Japan)
• OSTI ID: 6799460
• Journal Information: J. Comput. Assist. Tomogr.; (United States), Journal Name: J. Comput. Assist. Tomogr.; (United States) Vol. 12:5; ISSN JCATD
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOPSY
BODY
CARBON 11
CARBON ISOTOPES
CARBOXYLIC ACIDS
CARCINOMAS
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
ISOTOPES
LIGHT NUCLEI
LIPOTROPIC FACTORS
LUNGS
METHIONINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
RADIOISOTOPES
RESPIRATORY SYSTEM
TOMOGRAPHY