Cerebral blood flow and autoregulation during hypothermic cardiopulmonary bypass
Journal Article
·
· Ann. Thorac. Surg.; (United States)
Mean hemispheric cerebral blood flow (CBF) was studied following intravenous or intraarterial administration of xenon-133, in 10 men admitted for coronary artery bypass grafting. Repeated CBF measurements were performed to evaluate autoregulation before, during, and after cardiopulmonary bypass (CPB). During CPB mean CBF remained unchanged compared with the pre-CPB level, without evidence of cerebral hyperemia or impairment of autoregulation. A marked increase in CBF occurred after CPB and was followed by a time-dependent reduction toward the pre-CPB level. The data support the alpha-stat regulation theory but cannot explain the cerebral vasodilation observed after CPB.
- Research Organization:
- Univ. Hospital, Lund, Sweden
- OSTI ID:
- 6790989
- Journal Information:
- Ann. Thorac. Surg.; (United States), Journal Name: Ann. Thorac. Surg.; (United States) Vol. 4; ISSN ATHSA
- Country of Publication:
- United States
- Language:
- English
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Journal Article
·
Mon Mar 31 23:00:00 EST 1986
· Ann. Thorac. Surg.; (United States)
·
OSTI ID:5741946
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Journal Article
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Fri Sep 01 00:00:00 EDT 1989
· Circulation; (USA)
·
OSTI ID:5411865
Cerebral blood flow decreases with time whereas cerebral oxygen consumption remains stable during hypothermic cardiopulmonary bypass in humans
Journal Article
·
Thu Jan 31 23:00:00 EST 1991
· Anesthesia and Analgesia (Cleveland) (Current Researches); (USA)
·
OSTI ID:5986950
Related Subjects
550600 -- Medicine
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BLOOD VESSELS
BODY
BRAIN
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
CORONARIES
DAYS LIVING RADIOISOTOPES
DYNAMIC FUNCTION STUDIES
EVEN-ODD NUCLEI
GRAFTS
HOMEOSTASIS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NERVOUS SYSTEM
NUCLEI
ORGANS
RADIOISOTOPES
SURGERY
TIME DEPENDENCE
TRANSPLANTS
VASODILATION
XENON 133
XENON ISOTOPES
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BLOOD VESSELS
BODY
BRAIN
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
CORONARIES
DAYS LIVING RADIOISOTOPES
DYNAMIC FUNCTION STUDIES
EVEN-ODD NUCLEI
GRAFTS
HOMEOSTASIS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NERVOUS SYSTEM
NUCLEI
ORGANS
RADIOISOTOPES
SURGERY
TIME DEPENDENCE
TRANSPLANTS
VASODILATION
XENON 133
XENON ISOTOPES