Patterns of failure and results of preoperative irradiation vs radiation therapy alone in carcinoma of the pyriform sinus

Conference · Mon Sep 01 04:00:00 EDT 1980 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

OSTI ID:6784135

Byhardt, R W ^[1]; Cox, J D

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1. Veterans Administration Medical Center, WI

From 1968 to 1977, 53 of 78 patients with carcinoma of the pyriform sinus completed planned therapy and were eligible for followup a minimum of two years. Of the 53, 35 (66%) were treated with high dose preoperative irradiation and surgery, while 18 (33%) were treated with radiation therapy alone. The radiation therapy fields for both groups were reviewed for adequacy of coverage of the known and potential tumor volume and of all the failures in the primary site and nodes, 17% were felt to be at the margin of the irradiated field. There was a 34% (12 of 35) rate of pharyngocutaneous fistulae with the combined therapy. Three of the 12 fistulae were a result of recurrent tumor and 2 of these had carotid rupture.

• OSTI ID: 6784135
• Conference Information: Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Journal Volume: 6:9
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ARTERIES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLOOD VESSELS
BODY
BODY AREAS
CARCINOMAS
CARDIOVASCULAR SYSTEM
CAROTID ARTERIES
COMPARATIVE EVALUATIONS
DELAYED RADIATION EFFECTS
DIGESTIVE SYSTEM
DISEASES
ESOPHAGUS
FAILURES
FISTULAE
LARYNX
MEDICINE
METASTASES
NECK
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
PHARYNX
PNEUMONITIS
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
RUPTURES
SIDE EFFECTS
SURGERY
SURVIVAL TIME
THERAPY