Missouri University Multi-Plane Imager (MUMPI): A high sensitivity rapid dynamic ECT brain imager

Conference · Sun Jan 01 00:00:00 EST 1984 · J. Nucl. Med.; (United States)

OSTI ID:6779953

Logan, K W; Holmes, R A

The authors have designed a unique ECT imaging device that can record rapid dynamic images of brain perfusion. The Missouri University Multi-Plane Imager (MUMPI) uses a single crystal detector that produces four orthogonal two-dimensional images simultaneously. Multiple slice images are reconstructed from counts recorded from stepwise or continuous collimator rotation. Four simultaneous 2-d image fields may also be recorded and reviewed. The cylindrical sodium iodide crystal and the rotating collimator concentrically surround the source volume being imaged with the collimator the only moving part. The design and function parameters of MUMPI have been compared to other competitive tomographic head imaging devices. MUMPI's principal advantages are: 1) simultaneous direct acquisition of four two-dimensional images; 2) extremely rapid project set acquisition for ECT reconstruction; and 3) instrument practicality and economy due to single detector design and the absence of heavy mechanical moving components (only collimator rotation is required). MUMPI should be ideal for imaging neutral lipophilic chelates such as Tc-99m-PnAO which passively diffuses across the intact blood-brain-barrier and rapidly clears from brain tissue.

• Research Organization: Univ. of Missouri, Columbia, MO
• OSTI ID: 6779953
• Report Number(s): CONF-840619-; TRN: 87-008882
• Journal Information: J. Nucl. Med.; (United States), Vol. 25:5; Conference: 31. annual meeting of the Society of Nuclear Medicine, Los Angeles, CA, USA, 5 Jun 1984
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
BRAIN
EMISSION COMPUTED TOMOGRAPHY
CRYSTAL COUNTERS
IMAGE PROCESSING
NAI DETECTORS
DESIGN
ANIMAL TISSUES
BLOOD
COLLIMATORS
COMPARATIVE EVALUATIONS
DIFFUSION
IMAGES
ROTATION
SENSITIVITY
TECHNETIUM 99
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
MEASURING INSTRUMENTS
MOTION
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PROCESSING
RADIATION DETECTORS
RADIOISOTOPES
SCINTILLATION COUNTERS
SOLID SCINTILLATION DETECTORS
TECHNETIUM ISOTOPES
TISSUES
TOMOGRAPHY
YEARS LIVING RADIOISOTOPES
550602* - Medicine- External Radiation in Diagnostics- (1980-)
440101 - Radiation Instrumentation- General Detectors or Monitors & Radiometric Instruments