Free and microvascular bone grafting in the irradiated dog mandible
Journal Article
·
· J. Oral Maxillofac. Surg.; (United States)
Microvascular and free rib grafts were placed in 4.5 cm defects in an edentate mandibular body defect 18 to 28 days after completion of 50 Gy of irradiation from a /sup 60/Co source. The animals were sacrificed from two to forty weeks postoperatively and evaluated clinically, radiographically, and histologically. There was a marked difference in the alveolar mucosal viability with the two grafts. Mucosal dehiscence was not observed over any of the microvascular grafts, but was present in seven-eighths of the free grafts. Union of the microvascular bone graft to the host bone occurred within six weeks. In contrast, after six weeks the free graft was sequestered in all the animals. An unexpected finding with both types of graft was the marked subperiosteal bone formation. This bone appeared to be derived from the host bed, stabilizing and bridging the defects bilaterally. The results suggest that radiated periosteum may play an important role in osteogenesis.
- Research Organization:
- Harvard School of Dental Medicine, Boston, MA
- OSTI ID:
- 6777119
- Journal Information:
- J. Oral Maxillofac. Surg.; (United States), Journal Name: J. Oral Maxillofac. Surg.; (United States) Vol. 1; ISSN JOMSD
- Country of Publication:
- United States
- Language:
- English
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Journal Article
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Wed Oct 31 23:00:00 EST 1984
· Ann. Plast. Surg.; (United States)
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OSTI ID:5963880
Bone scintigraphy in evaluating the viability of composite bone grafts revascularized by microvascular anastomoses, conventional autogenous bone grafts, and free non-revascularized periosteal grafts
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Thu Jul 01 00:00:00 EDT 1982
· J. Bone Jt. Surg., Am. Vol.; (United States)
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OSTI ID:6718410
Reconstruction of mandibular defects after radiation, using a free, living bone, graft transferred by microvascular anastomoses. An experimental study
Journal Article
·
Thu May 01 00:00:00 EDT 1975
· Plast. Reconstr. Surg., v. 55, no. 5, pp. 563-572
·
OSTI ID:4021014
Related Subjects
560120* -- Radiation Effects on Biochemicals
Cells
& Tissue Culture
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BODY
COBALT 60
COBALT ISOTOPES
DISEASES
DOGS
DOSES
GRAFT-HOST REACTION
GRAFTS
HEALING
INJURIES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
JAW
MAMMALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
ORGANS
RADIATION DOSES
RADIOISOTOPES
RECOVERY
SKELETAL DISEASES
SKELETON
SKULL
TRANSPLANTS
VERTEBRATES
WOUNDS
YEARS LIVING RADIOISOTOPES
Cells
& Tissue Culture
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BODY
COBALT 60
COBALT ISOTOPES
DISEASES
DOGS
DOSES
GRAFT-HOST REACTION
GRAFTS
HEALING
INJURIES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
JAW
MAMMALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
ORGANS
RADIATION DOSES
RADIOISOTOPES
RECOVERY
SKELETAL DISEASES
SKELETON
SKULL
TRANSPLANTS
VERTEBRATES
WOUNDS
YEARS LIVING RADIOISOTOPES