Use of short-term bioassays in estimating human health hazards of waste-water effluents
Effluents from waste-water treatment facilities are discharged as a complex mixture of numerous chemical substances, which may include cytotoxic, carcinogenic, and mutagenic compounds. The U.S. Environmental Protection Agency has recently established a research program to determine if a bioassay approach for evaluating the potential adverse human health effects from exposure to complex mixtures might supplement conventional chemical analysis for setting regulatory limits for waste waters. This paper summarizes a bioassay testing strategy for characterizing cytotoxic and mutagenic activity of various waste water effluents. The use of a relative potency framework for assessing complex mixtures for potential health hazards is addressed.
- Research Organization:
- Environmental Protection Agency, Cincinnati, OH (USA). Health Effects Research Lab.
- OSTI ID:
- 6767981
- Report Number(s):
- PB-88-220686/XAB; EPA-600/D-88/132
- Country of Publication:
- United States
- Language:
- English
Similar Records
Application of a simple short-term bioassay for the identification of genotoxins from hazardous wastes
Bioassays for estimating health hazards of new energy technologies
Related Subjects
Aquatic-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOASSAY
CARCINOGENS
CHEMICAL EFFLUENTS
DISPERSIONS
HAZARDOUS MATERIALS
HAZARDS
HEALTH HAZARDS
HYDROGEN COMPOUNDS
LIQUID WASTES
MATERIALS
MIXTURES
MUTAGENS
OXYGEN COMPOUNDS
REGULATIONS
RISK ASSESSMENT
WASTE WATER
WASTES
WATER