Bioassays for estimating health hazards of new energy technologies
The Lawrence Livermore Laboratory is developing a number of bioassays to determine whether the effluents of in situ shale-oil and coal-gas recovery processes contain genetic toxicants - substances that may modify the genetic material of cells and thereby cause mutations leading to cancer. The procedure is to obtain water from wells near the in situ experiments, concentrate it, fractionate it into chemical classes, and test each fraction with a series of bioassays. In this series of tests, bacteria are used to screen the substances for mutagenic activity, animal cell-cultures to confirm the activity, and whole animals to approximate mutagenic activity in humans. Results to date indicate that these bioassays are sensitive enough to detect small amounts of potentially hazardous substances in dilute effluents.
- OSTI ID:
- 5988320
- Journal Information:
- Energy Technol. Rev.; (United States), Journal Name: Energy Technol. Rev.; (United States); ISSN ETERD
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BACTERIA
BIOASSAY
BITUMINOUS MATERIALS
CARBONACEOUS MATERIALS
CARCINOGENS
CHEMICAL REACTIONS
COAL GASIFICATION
DECOMPOSITION
ENERGY SOURCES
FOSSIL FUELS
FUELS
GASIFICATION
HAZARDS
HEALTH HAZARDS
HYDROGEN COMPOUNDS
IN-SITU GASIFICATION
IN-SITU PROCESSING
IN-SITU RETORTING
LAWRENCE LIVERMORE LABORATORY
LIQUID WASTES
MATERIALS
MICROORGANISMS
MUTAGEN SCREENING
NATIONAL ORGANIZATIONS
OIL SHALES
OXYGEN COMPOUNDS
PROCESSING
RESEARCH PROGRAMS
RETORTING
SCREENING
THERMOCHEMICAL PROCESSES
US AEC
US DOE
US ERDA
US ORGANIZATIONS
WASTE WATER
WASTES
WATER