Reference dose rates for single- and double-plane /sup 192/Ir implants

Journal Article · Sun May 01 04:00:00 EDT 1988 · Med. Phys.; (United States)

OSTI ID:6766937

Saw, C B; Suntharalingam, N

The proper selection of the reference dose rate is critical in the irradiation of a tumor or tumor bed using interstitial implant. The selected reference dose rate should result in the delivery of highly homogeneous dose throughout the target volume, adequately cover the target volume, and minimize irradiation of the surrounding normal tissues. In this paper, the influence of the reference dose rate on the adequacy of the irradiation of idealized target volumes using single- and double-plane /sup 192/Ir implants was studied in terms of three volumetric irradiation indices. The results show that maximum relative dose homogeneity can be attained if the proper reference dose rate is chosen. This isodose rate contour exhibits a width larger than the thickness of the target volume in the central plane. The lowest dose rate within the idealized target volume is not recommended as the reference dose rate to avoid a large volume of the surrounding tissues from receiving dose rates equal to or greater than this dose rate, and also the inhomogeneous irradiation of the target volume.

• Research Organization: Thomas Jefferson Univ. Hospital, Philadelphia, PA (USA)
• OSTI ID: 6766937
• Journal Information: Med. Phys.; (United States), Journal Name: Med. Phys.; (United States) Vol. 15:3; ISSN MPHYA
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
DAYS LIVING RADIOISOTOPES
DOSE-RESPONSE RELATIONSHIPS
DOSES
ELECTRON CAPTURE RADIOISOTOPES
HEAVY NUCLEI
IMPLANTS
INTERNAL CONVERSION RADIOISOTOPES
IRIDIUM 192
IRIDIUM ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MINUTES LIVING RADIOISOTOPES
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
PLANNING
RADIATION DOSES
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
THERAPY
YEARS LIVING RADIOISOTOPES