Planning of Ir-192 seed implants for boost irradiation to the breast

Journal Article · Sun Dec 01 04:00:00 EST 1985 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(85)90099-9· OSTI ID:5618205

Zwicker, R D; Schmidt-Ullrich, R; Schiller, B

The conservative management of early stage breast cancer with tumor excision and irradiation of the breast is becoming increasingly accepted as an alternative to modified radical mastectomy. The radiotherapy typically consists of 45 to 50 Gy delivered with external beam irradiation, followed by boost irradiation of 15 to 20 Gy to the tumor bed using electron beams or interstitial implantation. Pathological evaluation of the excised tumor, clinical assessment, and mammography are used to determine the tissue volume potentially containing a residual tumor burden and therefore requiring boost irradiation. In this paper we describe planning and implantation procedures for Quimby-type breast implants using Ir-192 seeds encapsulated in nylon tubing. This system deviates in several important respects from the requirements of the standard brachytherapy systems. For double-plane implants, optimized values of the interplanar spacing are given for a range of implant sizes, along with the corresponding target dose rates for 1.0 mCi seeds. We also describe a modification of the angiocatheter implantation technique, which allows the radioactive sources to be secured in place by a magnetic cap and washer, thus greatly facilitating the removal of the sources at the end of treatment.

• OSTI ID: 5618205
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 12; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BEAMS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
CARCINOMAS
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON BEAMS
ELECTRON CAPTURE RADIOISOTOPES
GLANDS
HEAVY NUCLEI
IMPLANTS
INTERNAL CONVERSION RADIOISOTOPES
IRIDIUM 192
IRIDIUM ISOTOPES
IRRADIATION PROCEDURES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEPTON BEAMS
MAMMARY GLANDS
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PARTICLE BEAMS
PLANNING
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY
YEARS LIVING RADIOISOTOPES