Abnormal Tc-99m-MDP/GA-67 scan patterns in association with active chronic osteomyelitis
In this study the authors reviewed data from 136 patients (pts) in order to refine the interpretive criteria used to diagnose active osteomyelitis (AOM) in patients with previous bone disease (e.g., old osteomyelitis, fractures, orthopedic devices excluding prostheses). They evaluated bone (Tc-99mMDP) and gallium 67 studies and obtained followup in all pts. AOM was diagnosed by surgery or biopsy and culture in 49 pts and was excluded by the same criteria in 16 pts. An additional 71 pts had the diagnosis excluded by followup clinical criteria. Five patterns were found. T1: abnormal Tc-99m-MDP, normal Ga-67. T2: diffuse increased uptake of both radiopharmaceuticals with Tc-99m-MDP greater than Ga-67. T3: different geographic distribution, but similar intensities of uptake of both. T4: very similar uptake and distribution of both. T5: Ga-67 exceeded Tc-99m-MDP. The authors conclude that T5 is diagnostic of AOM, T3 and T4 raise the probability of AOM than before scanning, T1 and T2 decrease it.
- Research Organization:
- Harvard Medical School, Boston, MA
- OSTI ID:
- 6759823
- Report Number(s):
- CONF-850611-
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 26:5; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BONE FRACTURES
BONE TISSUES
CONNECTIVE TISSUE
CORRELATIONS
COUNTING TECHNIQUES
DATA ANALYSIS
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DISTRIBUTION
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EVALUATION
GALLIUM 67
GALLIUM ISOTOPES
HOURS LIVING RADIOISOTOPES
INJURIES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MEDICAL SUPPLIES
NUCLEI
ODD-EVEN NUCLEI
OSTEOMYELITIS
PROSTHESES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIONUCLIDE KINETICS
RADIOPHARMACEUTICALS
SCINTISCANNING
SKELETAL DISEASES
TECHNETIUM 99
TECHNETIUM ISOTOPES
TISSUE DISTRIBUTION
TISSUES
UPTAKE
YEARS LIVING RADIOISOTOPES