Evidence for two conductance/exchange pathways for chloride in rat parotid secretory granules
Journal Article
·
· Biochem. Biophys. Res. Commun.; (United States)
Electron probe x-ray microanalysis was used to determine that bromide is localized to rat parotid secretory granules at early stages of an in situ Cl/Br washout experiment. Chloride efflux and bromide influx across the secretory granule membrane occurred with a time order of minutes. Since the Cl washout data indicated minimal Cl binding within the granule, and therefore minimal Br binding, the Br localization results suggest the presence of two or more anion conductance/exchange pathways in the granule membrane for the Cl (Br) ion.
- Research Organization:
- Univ. of Washington, Seattle (USA)
- OSTI ID:
- 6758456
- Journal Information:
- Biochem. Biophys. Res. Commun.; (United States), Journal Name: Biochem. Biophys. Res. Commun.; (United States) Vol. 155:2; ISSN BBRCA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Regulated phosphorylation of secretory granule membrane proteins of the rat parotid gland
Isolated secretion granules from parotid glands of chronically stimulated rats possess an alkaline internal pH and inward-directed H/sup +/ pump activity
Effects of 5-fluorouracil on the secretory process of the rat parotid gland
Journal Article
·
Sun Jul 01 00:00:00 EDT 1990
· American Journal of Physiology; (USA)
·
OSTI ID:6642889
Isolated secretion granules from parotid glands of chronically stimulated rats possess an alkaline internal pH and inward-directed H/sup +/ pump activity
Journal Article
·
Wed Oct 01 00:00:00 EDT 1986
· J. Cell Biol.; (United States)
·
OSTI ID:6477236
Effects of 5-fluorouracil on the secretory process of the rat parotid gland
Thesis/Dissertation
·
Tue Dec 31 23:00:00 EST 1985
·
OSTI ID:6792187
Related Subjects
550201* -- Biochemistry-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
BIOLOGICAL LOCALIZATION
BIOLOGICAL PATHWAYS
BODY
BROMIDES
BROMINE COMPOUNDS
CELL CONSTITUENTS
CELL MEMBRANES
CHEMICAL ANALYSIS
CHEMICAL BONDS
CHLORIDES
CHLORINE COMPOUNDS
ELECTRIC CONDUCTIVITY
ELECTRICAL PROPERTIES
ELECTROMAGNETIC RADIATION
ELECTRON MICROPROBE ANALYSIS
GLANDS
HALIDES
HALOGEN COMPOUNDS
IONIZING RADIATIONS
MAMMALS
MEMBRANE TRANSPORT
MEMBRANES
MICROANALYSIS
ORGANS
PHYSICAL PROPERTIES
RADIATIONS
RATS
RODENTS
SALIVARY GLANDS
VERTEBRATES
X RADIATION
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
BIOLOGICAL LOCALIZATION
BIOLOGICAL PATHWAYS
BODY
BROMIDES
BROMINE COMPOUNDS
CELL CONSTITUENTS
CELL MEMBRANES
CHEMICAL ANALYSIS
CHEMICAL BONDS
CHLORIDES
CHLORINE COMPOUNDS
ELECTRIC CONDUCTIVITY
ELECTRICAL PROPERTIES
ELECTROMAGNETIC RADIATION
ELECTRON MICROPROBE ANALYSIS
GLANDS
HALIDES
HALOGEN COMPOUNDS
IONIZING RADIATIONS
MAMMALS
MEMBRANE TRANSPORT
MEMBRANES
MICROANALYSIS
ORGANS
PHYSICAL PROPERTIES
RADIATIONS
RATS
RODENTS
SALIVARY GLANDS
VERTEBRATES
X RADIATION