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Identification and localization of microsatellite markers covering human chromosome 18

Journal Article · · Genomics; (United States)
; ; ; ;  [1]; ;  [2]
  1. Thomas Jefferson Univ., Philadelphia, PA (United States)
  2. Columbia Univ., New York, NY (United States)
To generate microsatellite markers from chromosome 18, the authors have cytogenetically localized a large number of [lambda] phage using a deletion mapping panel of somatic cell hybrids. Here they describe the identification of 65 new CA-repeat-containing phage and the localization of five markers developed in other laboratories. This approach allows the selection of a subset of markers that are well spaced across the chromosome and can be developed as genetic markers. The use of PCR-based markers should allow for the rapid genomic screening of disease genes on chromosome 18. 11 refs., 1 fig., 1 tab.
OSTI ID:
6758453
Journal Information:
Genomics; (United States), Journal Name: Genomics; (United States) Vol. 14:4; ISSN GNMCEP; ISSN 0888-7543
Country of Publication:
United States
Language:
English

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