Method for improved selectivity in photo-activation of molecular agents
A method for the treatment of a particular volume of plant or animal tissue comprising the steps of treating the plant or animal tissue with at least one photo-active molecular agent, wherein the particular volume of the plant or animal tissue retains at least a portion of the at least one photo-active molecular agent, and then treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of at least one of the at least one photo-active molecular agent retained in the particular volume of the plant or animal tissue, wherein the at least one photo-active molecular agent becomes active in the particular volume of the plant or animal tissue. There is also disclosed a method for the treatment of cancer in plant or animal tissue and a method for producing at least one photo-activated molecular agent in a particular volume of a material. 23 figs.
- Research Organization:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- AC05-84OR21400
- Assignee:
- Photogen, Inc., Knoxville, TN (United States)
- Patent Number(s):
- US 5,829,448/A/
- Application Number:
- PAN: 8-739,801
- OSTI ID:
- 675825
- Resource Relation:
- Other Information: PBD: 3 Nov 1998
- Country of Publication:
- United States
- Language:
- English
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Method for improved selectivity in photo-activation of molecular agents
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