Chemical characterization of a polar portion in the neutral fraction derived from airborne particulate extracts responsible for the embryotoxicity in the chicken embryo
Journal Article
·
· J. Toxicol. Environ. Health; (United States)
Airborne particulate matter was collected with a high-volume air sampler between June 1984 and May 1985 on the roof top of the authors institute. The tar material extracted was separated into six fractions by liquid-liquid partition and silica gel column chromatography. These fractions were then tested for their embryotoxicities by a chicken embryo assay. A moderately polar fraction per weight and a fraction containing polycyclic aromatic hydrocarbons (PAHs) had the greatest toxicity for chicken embryos. When the polar fraction was purified by high-pressure liquid chromatography, the purified fraction was 3.7 times more toxic than the original polar fraction. To determine the responsible components for the toxicity, the purified fraction as well as the original fraction was analyzed by capillary gas chromatography and gas chromatography-mass spectrometry. The characterized components were classified into oxygenated PAHs (containing ketones, quinones, and aldehydes), nitrogen-containing PAHS, diphenyl-substituted aliphatic ketones (or diketones), and esters of aliphatic acids.
- Research Organization:
- Osaka Prefectural Institute of Public Health (Japan)
- OSTI ID:
- 6744408
- Journal Information:
- J. Toxicol. Environ. Health; (United States), Journal Name: J. Toxicol. Environ. Health; (United States) Vol. 24:4; ISSN JTEHD
- Country of Publication:
- United States
- Language:
- English
Similar Records
Toxicity to chicken embryos of organic extracts from airborne particulates separated into five sizes
Embryotoxic effects of eight organic peroxides and hydrogen peroxide on three-day chicken embryos
Embryotoxicity of extracts from Lake Ontario rainbow trout (Oncorhynchus mykiss) to Japanese medaka (Oryzias latipes)
Journal Article
·
Fri Jul 01 00:00:00 EDT 1988
· Bull. Environ. Contam. Toxicol.; (United States)
·
OSTI ID:6647861
Embryotoxic effects of eight organic peroxides and hydrogen peroxide on three-day chicken embryos
Journal Article
·
Tue Jan 31 23:00:00 EST 1984
· Environ. Res.; (United States)
·
OSTI ID:6903233
Embryotoxicity of extracts from Lake Ontario rainbow trout (Oncorhynchus mykiss) to Japanese medaka (Oryzias latipes)
Journal Article
·
Thu Sep 01 00:00:00 EDT 1994
· Environmental Toxicology and Chemistry; (United States)
·
OSTI ID:7173186
Related Subjects
500200 -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AROMATICS
BIOASSAY
BIRDS
CHEMICAL ANALYSIS
CHICKENS
CHROMATOGRAPHY
EMBRYOS
FOWL
GAS CHROMATOGRAPHY
HYDROCARBONS
MASS SPECTROSCOPY
ORGANIC COMPOUNDS
PARTICLES
PARTICULATES
POLYCYCLIC AROMATIC HYDROCARBONS
SAMPLING
SENSITIVITY
SEPARATION PROCESSES
SPECTROSCOPY
TOXICITY
VERTEBRATES
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AROMATICS
BIOASSAY
BIRDS
CHEMICAL ANALYSIS
CHICKENS
CHROMATOGRAPHY
EMBRYOS
FOWL
GAS CHROMATOGRAPHY
HYDROCARBONS
MASS SPECTROSCOPY
ORGANIC COMPOUNDS
PARTICLES
PARTICULATES
POLYCYCLIC AROMATIC HYDROCARBONS
SAMPLING
SENSITIVITY
SEPARATION PROCESSES
SPECTROSCOPY
TOXICITY
VERTEBRATES