Cerebral abnormalities: use of calculated T1 and T2 magnetic resonance images for diagnosis

Journal Article · Sun Jan 01 04:00:00 EST 1984 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.150.1.6689792· OSTI ID:6743533

Mills, C M; Crooks, L E; Kaufman, L; Brant-Zawadzki, M

The potential clinical importance of T1 and T2 relaxation times in distinguishing normal and pathologic tissue with magnetic resonance (MR) is discussed and clinical examples of cerebral abnormalities are given. Five patients with cerebral infarction, 15 with multiple sclerosis, two with Wilson disease, and four with tumors were imaged. Hemorrhagic and ischemic cerebrovascular accidents were distinguished using the spin echo technique. In the patients with multiple sclerosis, lesions had prolonged T1 and T2 times, but the definition of plaque was limited by spatial resolution. No abnormalities in signal intensity were seen in the patient with Wilson disease who was no longer severly disabled; abnormal increased signal intensity in the basal ganglia was found in the second patient with Wilson disease. Four tumors produced abnormal T1 and T2 relaxation times but these values alone were not sufficient for tumor characterization.

• Research Organization: Univ. of California, San Francisco
• OSTI ID: 6743533
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 150:1; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
BRAIN
CARDIOVASCULAR DISEASES
CENTRAL NERVOUS SYSTEM
CEREBRUM
DIAGNOSIS
DISEASES
HEMORRHAGE
ISCHEMIA
MAGNETIC RESONANCE
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MAGNETIC RESONANCE
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
RELAXATION TIME
RESONANCE
SPIN ECHO
SYMPTOMS
VASCULAR DISEASES