In-vivo measurement of lithium in the brain and other organs

Patent · 26 August 1983

OSTI ID:6726654

Vartsky, D; Wielopolski, L; LoMonte, A F; Ellis, K J; Cohn, S H

An in-vivo method of measurement of the amount of lithium present in tissue and organs of breathing animals is described. The basis for the technique is the lithium-1 neutron interaction - /sup 6/Li(n,..cap alpha..)T. The lithium is irradiated with thermal neutrons to produce tritium atoms. The tritium diffuses into the tissues and is exhaled. By measuring the amount of tritium exhaled, the lithium concentration in the irradiated zone is determined.

• DOE Contract Number: AC02-76CH00016
• Assignee: Dept. of Energy
• Patent Number(s): None
• Application Number: ON: DE84014668
• OSTI ID: 6726654
• Country of Publication: United States
• Language: English

Related Subjects

550501 -- Metabolism-- Tracer Techniques
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ALKALI METAL ISOTOPES
ALKALI METALS
ALPHA PARTICLES
BARYON REACTIONS
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CHARGED PARTICLES
CLEARANCE
DIRECT REACTIONS
DISTRIBUTION
ELEMENTARY PARTICLES
ELEMENTS
EXCRETION
FERMIONS
HADRON REACTIONS
HADRONS
HYDROGEN ISOTOPES
IN VIVO
ISOTOPES
LIGHT NUCLEI
LITHIUM
LITHIUM 6
LITHIUM 6 TARGET
LITHIUM ISOTOPES
LUNG CLEARANCE
MEASURING METHODS
METALS
NEUTRON REACTIONS
NEUTRONS
NUCLEAR REACTIONS
NUCLEI
NUCLEON REACTIONS
NUCLEONS
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
PICKUP REACTIONS
QUANTITY RATIO
RADIOACTIVATION
RADIOISOTOPES
STABLE ISOTOPES
TARGETS
TISSUE DISTRIBUTION
TRANSFER REACTIONS
TRITIUM
YEARS LIVING RADIOISOTOPES