In-vivo measurement of lithium in the brain and other organs

Patent · Fri Aug 26 00:00:00 EDT 1983

OSTI ID:6726654

Vartsky, D; Wielopolski, L; LoMonte, A F; Ellis, K J; Cohn, S H

An in-vivo method of measurement of the amount of lithium present in tissue and organs of breathing animals is described. The basis for the technique is the lithium-1 neutron interaction - /sup 6/Li(n,..cap alpha..)T. The lithium is irradiated with thermal neutrons to produce tritium atoms. The tritium diffuses into the tissues and is exhaled. By measuring the amount of tritium exhaled, the lithium concentration in the irradiated zone is determined.

• DOE Contract Number: AC02-76CH00016
• Assignee: Dept. of Energy
• Application Number: ON: DE84014668
• OSTI ID: 6726654
• Resource Relation: Other Information: Portions are illegible in microfiche products
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
LITHIUM
MEASURING METHODS
TISSUE DISTRIBUTION
ALPHA PARTICLES
IN VIVO
LITHIUM 6
LITHIUM 6 TARGET
LUNG CLEARANCE
NEUTRON REACTIONS
NEUTRONS
PICKUP REACTIONS
QUANTITY RATIO
RADIOACTIVATION
TRITIUM
ALKALI METAL ISOTOPES
ALKALI METALS
BARYON REACTIONS
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CHARGED PARTICLES
CLEARANCE
DIRECT REACTIONS
DISTRIBUTION
ELEMENTARY PARTICLES
ELEMENTS
EXCRETION
FERMIONS
HADRON REACTIONS
HADRONS
HYDROGEN ISOTOPES
ISOTOPES
LIGHT NUCLEI
LITHIUM ISOTOPES
METALS
NUCLEAR REACTIONS
NUCLEI
NUCLEON REACTIONS
NUCLEONS
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
RADIOISOTOPES
STABLE ISOTOPES
TARGETS
TRANSFER REACTIONS
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550501 - Metabolism- Tracer Techniques