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Carcinoma of the prostate: results of post-irradiation biopsy

Journal Article · · Prostate (N.Y.); (United States)
;
One hundred and forty-six patients with clinically localized carcinoma of the prostate were surgically staged and treated with external beam irradiation to the prostate and to the lymph node-bearing areas. Sixty-four (44%) of these patients had needle biopsy of the prostate 18 months or more following completion of therapy. Thirty-nine (61%) of the biopsies were interpreted as positive and 25 (39%) as negative. Twenty-eight (72%) of the 39 patients with a positive biopsy have subsequently developed metastases as compared to only 6 of 25 (24%) of the patients with a negative biopsy. It is concluded that an apparently positive postirradiation biopsy is likely to indicate active disease and identifies patients at a higher risk for development of metastases. Other details of staging, grading, and outcomes that compare these two groups are discussed.
Research Organization:
Stanford Univ. School of Medicine, CA
OSTI ID:
6724378
Journal Information:
Prostate (N.Y.); (United States), Journal Name: Prostate (N.Y.); (United States) Vol. 5:1; ISSN PRSTD
Country of Publication:
United States
Language:
English

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Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOPSY
BODY
CARCINOMAS
DIAGNOSTIC TECHNIQUES
DISEASES
EVALUATION
EXTERNAL IRRADIATION
GLANDS
IRRADIATION
MALE GENITALS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PROSTATE
RADIOLOGY
RADIOTHERAPY
SURVIVAL TIME
THERAPY