Ultrasonically guided 125iodine seed implantation with external radiation in management of localized prostatic carcinoma

Journal Article · Sun Oct 01 04:00:00 EDT 1989 · Urology (Ridgewood, N.J.); (USA)

DOI:https://doi.org/10.1016/0090-4295(89)90368-3· OSTI ID:5225885

Iversen, P; Bak, M; Juul, N; Laursen, F; von der Maase, H; Nielsen, L; Rasmussen, F; Torp-Pedersen, S; Holm, H H ^[1]

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1. Univ. of Copenhagen (Denmark)

Thirty-three patients with localized prostatic carcinoma (16 poorly differentiated) were treated with transperineal 125Iodine seed implantation (160 Gy) guided by transrectal ultrasonography and subsequent external beam irradiation (47.4 Gy). The observation time was six to sixty-eight months with a median follow-up of thirty-five months. Median change in prostatic volume was a reduction of 35 percent. Re-biopsy or transurethral resection of the prostate was performed in 25 patients after one to two years, revealing still malignant histology in 12 (48%). Development of distant metastases occurred in 14 patients (44%), and 8 have died of prostatic cancer. Fourteen patients suffered from late complications of which surgical intervention was indicated in 3 cases.

• OSTI ID: 5225885
• Journal Information: Urology (Ridgewood, N.J.); (USA), Journal Name: Urology (Ridgewood, N.J.); (USA) Vol. 34:4; ISSN URGYA; ISSN 0090-4295
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
CARCINOMAS
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GLANDS
IMPLANTS
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
MALE GENITALS
MEDICINE
METASTASES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
PROSTATE
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
THERAPY
ULTRASONOGRAPHY