Comparative toxicity of trivalent and hexavalent chromium. Alterations in blood and liver

Journal Article · Wed Feb 01 04:00:00 EST 1978 · Environ. Res.; (United States)

OSTI ID:6721965

Tandon, S K; Saxena, D K; Gaur, J S; Chandra, S V

The effects of trivalent and hexavalent chromium compounds on rabbits were studied with a view toward investigating the toxic potentials of two different forms of chromium to which industrial workers or miners might be exposed. While both forms of chromium altered the levels of certain important chemical constituents of blood and serum and produced significant morphological changes in the liver, the hexavalent form induced a greater effect. The accumulation of the metal was also higher in animals exposed to chromium in oxidation state 6 than in those exposed to metal in state 3.

• Research Organization: Industrial Toxicology Research Center, Lucknow, India
• OSTI ID: 6721965
• Journal Information: Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 15:1; ISSN ENVRA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL ACCUMULATION
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
CHEMICAL STATE
CHROMIUM
COMPARATIVE EVALUATIONS
DIGESTIVE SYSTEM
ELEMENTS
GLANDS
LIVER
MAMMALS
METALS
MORPHOLOGICAL CHANGES
ORGANS
RABBITS
TOXICITY
TRANSITION ELEMENTS
VALENCE
VERTEBRATES