Early-phase myocardial infarction: Evaluation by MR imaging

Conference · Sun Jun 01 04:00:00 EDT 1986 · Radiology; (United States)

OSTI ID:6719464

Tscholakoff, D; Higgins, C B; McNamara, M T; Derugin, N

In vivo gated magnetic resonance (MR) imaging was performed in 12 dogs immediately after occlusion of the left anterior descending coronary artery and serially up to 5 hours and again between 4 and 14 days. This was done to evaluate the appearance of acute myocardial infarcts and to determine how soon after coronary artery occlusion MR imaging can demonstrate the site of acute myocardial ischemia. In nine dogs with postmortem evidence of myocardial infarction, regional increase of signal intensity of the myocardium was present by 3 hours after coronary occlusion and conformed to the site of myocardial infarct found at autopsy. The signal intensity on T2-weighted images of the infarcted on T2-weighted images of the infarcted myocardium was significantly greater than that of normal myocardium at 3, 4, and 5 hours after occlusion. The T2 (spin-spin) relaxation time was significantly prolonged in the region of myocardial infarct at 3, 4, and 5 hours post-occlusion compared with normal myocardium. Myocardial wall thinning and increased intracavitary flow signal were found in six dogs with comparable pre- and postocclusion images in late systole.

• Research Organization: Dept. of Radiology, Univ. of California School of Medicine, San Francisco, CA 94143
• OSTI ID: 6719464
• Report Number(s): CONF-861136-
• Conference Information: Journal Name: Radiology; (United States) Journal Volume: 159:3
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
AUTOPSY
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
DETECTION
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DOGS
HEART
IMAGE PROCESSING
MAMMALS
MYOCARDIAL INFARCTION
NMR IMAGING
ORGANS
PROCESSING
RELAXATION TIME
VERTEBRATES