/sup 201/Tl-chloride thyroid scintigraphy to evaluate benign and/or malignant nodules: usefulness of the delayed scan
The purpose of this study is to evaluate benign and/or malignant thyroid tumors with /sup 201/Tl thyroid scan. Researchers studied 76 cases of histologically verified thyroid tumors, all seen as cold nodules on the /sup 123/I thyroid scan. /sup 201/Tl thyroid scan was performed 5-15 minutes (early scan) and 3-5 hours (delayed scan) after intravenous administration of 1.5-2.0 mCi of /sup 201/Tl. In 35 (94.6%) of 36 malignant tumors (anaplastic carcinoma, six; papillary carcinoma 23; follicular carcinoma, five; epidermoid carcinoma, one; malignant lymphoma, 1) /sup 201/Tl accumulated in the cold nodule of the /sup 123/I thyroid scan on both early and delayed scans. On the other hand, the delayed /sup 201/Tl scan was negative in 35 out of 39 (89.7%) benign tumors. Employing early and delayed /sup 201/Tl scans, researchers were able to differentiate most malignant thyroid tumors from those which were benign. False-negative and -positive cases are discussed.
- Research Organization:
- Osaka City University Medical School, Japan
- OSTI ID:
- 6718420
- Journal Information:
- Cancer (Philadelphia); (United States), Vol. 50:2
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
NEOPLASMS
DIAGNOSIS
THALLIUM 201
DIAGNOSTIC USES
THYROID
SCINTISCANNING
BIOLOGICAL LOCALIZATION
BIOPSY
BUILDUP
COMPARATIVE EVALUATIONS
HISTOLOGY
IODINE 123
PATIENTS
TIME DEPENDENCE
TUMOR CELLS
ANIMAL CELLS
BETA DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE GLANDS
GLANDS
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
THALLIUM ISOTOPES
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques