Tl-201 thyroid imaging in differentiating benign from malignant thyroid nodules
- College of Medicine, King Khalid University Hospital, King Saud University, Riyadh (Saudi Arabia)
To evaluate the value of Tl-201 thyroid imaging in differentiating benign from malignant thyroid nodules, 58 patients with histologically proven thyroid masses were studied. The nature of the thyroid tumor was initially assessed by Tc-99m scans. Early and delayed Tl-201 thyroid imaging were performed in all patients, and thallium uptake and clearance in the cold nodules were assessed visually. Of the 20 patients with histologically proven malignant nodules, 19 showed increased Tl-201 activity in both the early and delayed images, indicating a sensitivity of 95%. On the other hand, 35 out of the 38 patients with benign nodules showed no increased thallium activity in the nodules on the delayed images, indicating a specificity of 92%. When early thallium images were analyzed separately, the sensitivity was 100% but the specificity was only 37%. By combining early and delayed Tl-201 images, differentiation between benign and malignant cold nodules is feasible. False-positive and false-negative cases will be discussed.
- OSTI ID:
- 5189936
- Journal Information:
- Clinical Nuclear Medicine; (United States), Vol. 16:6; ISSN 0363-9762
- Country of Publication:
- United States
- Language:
- English
Similar Records
Thallium-201-chloride thyroid scintigraphy to evaluate benign and/or malignant nodules: usefulness of the delayed scan
Early and delayed thallium 201 imaging. Diagnosis of patients with cold thyroid nodules
Related Subjects
NEOPLASMS
DIAGNOSIS
THYROID
IMAGE PROCESSING
ISOMERIC NUCLEI
PATIENTS
SENSITIVITY ANALYSIS
SPECIFICITY
TECHNETIUM 99
THALLIUM 201
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE GLANDS
GLANDS
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PROCESSING
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
TECHNETIUM ISOTOPES
THALLIUM ISOTOPES
YEARS LIVING RADIOI
550601* - Medicine- Unsealed Radionuclides in Diagnostics