Study of RBE of Cf-252 of hemopoietic tissue and PLD-like effect of magnetic fields by CFU-S assay

Journal Article · Wed Jan 01 04:00:00 EST 1986 · Nucl. Sci. Appl.; (United States)

OSTI ID:6716491

Maruyama, Y; Magura, C; Feola, J

The RBE of Cf-252 (Cf) neutron irradiation was determined for hemopoietic tissue using spleen CFU-S. Radiosensitivity was compared to acute Cobalt-60 radiation and low dose rate (LDR) Cesium-137 under identical irradiation conditions. No dose rate effect was observed for hemopoietic CFU-S to acute or low dose rate photon irradiation. The RBE for CFU-S irradiated with Cf-252 either in vivo or in vitro was 2.1 for the neutron component of Cf irradiation. Potentially lethal damage (PLD) was studied for endogenous CFU-S using pulsating magnetic fields. Changes consistent with PLD-like effects were noted for Cf and acute Co-60 but not for LDR Cs-137 for the CFU-S.

• Research Organization: Univ. of Kentucky Medical Center, Radiation Therapy Oncology Center, Lexington, KY
• OSTI ID: 6716491
• Journal Information: Nucl. Sci. Appl.; (United States), Journal Name: Nucl. Sci. Appl.; (United States) Vol. 2:3; ISSN NSAPD
• Country of Publication: United States
• Language: English

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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALKALI METAL ISOTOPES
ALPHA DECAY RADIOISOTOPES
ANIMAL CELLS
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOASSAY
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CALIFORNIUM 252
CALIFORNIUM ISOTOPES
CESIUM 137
CESIUM ISOTOPES
COBALT 60
COBALT ISOTOPES
DAMAGING NEUTRON FLUENCE
DOSE RATES
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
EMISSION
EVEN-EVEN NUCLEI
GAMMA RADIATION
HEAVY NUCLEI
IN VITRO
IN VIVO
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LETHAL IRRADIATION
LOW DOSE IRRADIATION
MAGNETIC FIELDS
MASSLESS PARTICLES
MINUTES LIVING RADIOISOTOPES
NEUTRON EMISSION
NEUTRON FLUENCE
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
PHOTONS
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOSENSITIVITY
RBE
SOMATIC CELLS
SPLEEN CELLS
TISSUES
YEARS LIVING RADIOISOTOPES