Attenuation and detector response compensations used with Gibbs prior distributions for maximum A Posteriori SPECT reconstruction

Conference · Thu Oct 01 00:00:00 EDT 1992 · IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States)

OSTI ID:6716427

Lalush, D S; Tsui, B M.W. ^[1]

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1. Dept. of Radiology and Biomedical Engineering and MAthematics, Univ. of North Carolina, Chapel Hill, NC (United States)

In this paper, the authors study the relationship between the choice of parameters for a generalized Gibbs prior for the MAP-EM (Maximum A Posteriori, Expectation Maximization) algorithm, and the m model of the projection/backprojection process used in SPECT reconstruction. A realistic phantom, derived from an X-ray CT study and average Tl-201 uptake distributions in patients , was used n the investigation. simulated projection data including nonuniform attenuation, detector response, scatter, and Poisson noise were generated. From this data set, reconstructions were created using a MAP-EM technique with a generalized Gibbs prior, which is designed to smooth noise with minimal smoothing of edge information. the Gibbs prior has three adjustable parameters: one which determines the overall weight placed on the prior in the reconstruction process, and two others which affect the relative smoothing of noise and edges in the reconstructed image estimates.

• OSTI ID: 6716427
• Report Number(s): CONF-911106--
• Journal Information: IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States), Journal Name: IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States) Vol. 39:5; ISSN 0018-9499; ISSN IETNAE
• Country of Publication: United States
• Language: English

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