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Title: Comparison of 180{degree} and 360{degree} iterative reconstruction with non-uniform attenuation compensation for Tl-201 SPECT

Journal Article · · IEEE Transactions on Nuclear Science
DOI:https://doi.org/10.1109/23.467869· OSTI ID:148079
;  [1];  [2]
  1. Univ. of North Carolina, Chapel Hill, NC (United States)
  2. Univ. of California, San Francisco, CA (United States)

This study compares Tl-201 SPECT images reconstructed from 180{degree} and 360{degree} projection data, using iterative reconstruction with non-uniform attenuation compensation. Using a mathematical phantom of the human thorax, Monte Carlo simulation is used to produce both 180{degree} (45{degree} RAO to 45{degree} LPO) and 360{degree} Tl-201 SPECT projection data. Included in the simulation are the effects of non-uniform attenuation, detector response, scatter and statistical noise. The 180{degree} and 360{degree} data were taken over 64 and 128 angles, respectively, assuming the same total acquisition time for both. The simulated projection data were reconstructed with nonuniform attenuation compensation using the ML-EM algorithm for 50 iterations and, for comparison, were also reconstructed without attenuation compensation using the filtered backprojection method with a ramp filter. Transaxial slices of the reconstructed images, image profiles and Bull`s-eye plots all show that images reconstructed with attenuation compensation, unlike those reconstructed without attenuation compensation, are essentially the same within the region of the myocardium for the 180{degree} and 360{degree} data, with few artifacts and similar image contrast. Furthermore, for the same total imaging time, the images reconstructed from the 180` data have slightly less noise in the myocardial region.

OSTI ID:
148079
Report Number(s):
CONF-941061-; ISSN 0018-9499; TRN: 96:005807
Journal Information:
IEEE Transactions on Nuclear Science, Vol. 42, Issue 4Pt1; Conference: Institute of Electrical and Electronic Engineers (IEEE) nuclear science symposium and medical imaging conference, Norfolk, VA (United States), 30 Oct - 5 Nov 1994; Other Information: PBD: Aug 1995
Country of Publication:
United States
Language:
English