Comparison of 180{degree} and 360{degree} iterative reconstruction with non-uniform attenuation compensation for Tl-201 SPECT
- Univ. of North Carolina, Chapel Hill, NC (United States)
- Univ. of California, San Francisco, CA (United States)
This study compares Tl-201 SPECT images reconstructed from 180{degree} and 360{degree} projection data, using iterative reconstruction with non-uniform attenuation compensation. Using a mathematical phantom of the human thorax, Monte Carlo simulation is used to produce both 180{degree} (45{degree} RAO to 45{degree} LPO) and 360{degree} Tl-201 SPECT projection data. Included in the simulation are the effects of non-uniform attenuation, detector response, scatter and statistical noise. The 180{degree} and 360{degree} data were taken over 64 and 128 angles, respectively, assuming the same total acquisition time for both. The simulated projection data were reconstructed with nonuniform attenuation compensation using the ML-EM algorithm for 50 iterations and, for comparison, were also reconstructed without attenuation compensation using the filtered backprojection method with a ramp filter. Transaxial slices of the reconstructed images, image profiles and Bull`s-eye plots all show that images reconstructed with attenuation compensation, unlike those reconstructed without attenuation compensation, are essentially the same within the region of the myocardium for the 180{degree} and 360{degree} data, with few artifacts and similar image contrast. Furthermore, for the same total imaging time, the images reconstructed from the 180` data have slightly less noise in the myocardial region.
- OSTI ID:
- 148079
- Report Number(s):
- CONF-941061--
- Journal Information:
- IEEE Transactions on Nuclear Science, Journal Name: IEEE Transactions on Nuclear Science Journal Issue: 4Pt1 Vol. 42; ISSN 0018-9499; ISSN IETNAE
- Country of Publication:
- United States
- Language:
- English
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