Radioactive excretion in human milk following administration of /sup 99m/Tc macroaggregated albumin
Albumin-tagged sodium pertechnetate (technetium) is routinely used in nuclear medicine for scanning procedures of the lung. The rate of excretion of this radionuclide into breast milk and the resultant potential radiation hazard to the nursing infant have received little attention. Therefore the milk from a nursing mother who required a lung scan because of suspected pulmonary emboli using an intravenous injection of 4 mCi of /sup 99m/Tc macroaggregated human serum albumin was monitored. Albumin tagging severely limited the entrance of technetium into her milk and the radioactivity of the milk returned to base line by 24 hours. A total of 2.02 muCi of technetium was measured in the 24-hour milk collection after technetium injection and 94% of this amount was excreted by 15.5 hours. This amount of technetium administered orally to a newborn would deliver a total body radiation dose of .3 mrad. Therefore, an infant would receive trivial doses of radiation if breast-feeding were resumed 15.5 hours after administration of the radionuclide to the mother and nursing can clearly be resumed safely 24 hours after injection.
- Research Organization:
- Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH
- OSTI ID:
- 6711030
- Journal Information:
- Pediatrics; (United States), Vol. 70:2
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LUNGS
SCINTISCANNING
RADIATION HAZARDS
TECHNETIUM 99
DIAGNOSTIC USES
ALBUMINS
EXCRETION
INFANTS
ISOMERIC NUCLEI
MILK
RADIATION DOSES
RADIONUCLIDE KINETICS
SIDE EFFECTS
AGE GROUPS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CHILDREN
CLEARANCE
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DOSES
FOOD
HAZARDS
HEALTH HAZARDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PROTEINS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
560151 - Radiation Effects on Animals- Man