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Quantitative cerebral blood flow measurements using N-isopropyl-p-I-123-iodoamphetamine and single photon emission computed tomography with rotating gamma camera

Conference · · J. Nucl. Med.; (United States)
OSTI ID:6710710
; ; ; ; ;
The purpose of this study is to evaluate regional cerebral blood flow (rCBF) quantitatively using N-isopropyl-p-I-123-iodoamphetaine (IMP) and a single photon emission computed tomography (SPECT) with rotating gamma camera. Forty-six rCBF measurements were performed on 38 patients with cerebrovascular disorders. Arterial input sampling was performed for 5 min. after IMP injection. Projection data were collected from 35 to 59 min. after injection when activities in the brain became constant. These were corrected to represent 5 min. reference values using the monitored entire brain's time activity curve. rCBF values were calculated by reference sample method. The comparison study with IMP method and Xe-133 inhalation method was performed in 9 patients (119 cortical regions).
Research Organization:
Kanazawa Univ. Hospital, Kanazawa
OSTI ID:
6710710
Report Number(s):
CONF-850611-
Conference Information:
Journal Name: J. Nucl. Med.; (United States) Journal Volume: 26:5
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ALKYL RADICALS
AMPHETAMINES
ANALEPTICS
ARTERIES
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BLOOD VESSELS
BODY
BRAIN
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
CENTRAL NERVOUS SYSTEM AGENTS
CEREBRAL ARTERIES
CEREBRUM
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INHALATION
INJECTION
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IODINE 123
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOPROPYL RADICALS
ISOTOPES
MENTAL DISORDERS
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADICALS
RADIOISOTOPES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
SYMPATHOMIMETICS
TOMOGRAPHY
USES
VASCULAR DISEASES
XENON 133
XENON ISOTOPES