Radiation effects in the canine brain evaluated by quantitative computed tomography

Journal Article · Sun Aug 01 04:00:00 EDT 1982 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.144.3.7100479· OSTI ID:6702423

Fike, J R; Cann, C E; Davis, R L; Phillips, T L

Quantitative computed tomography (QCT) and histopathology were used to assess the effects of large single doses of x irradiation on the normal canine brain. Measurable changes demonstrated by QCT included increased contrast enhancement and enlargement of the lateral ventricles, which were observed prior to any clinical signs. The results suggest that QCT methods are effective in the noninvasive evaluation of radiation-induced brain injury.

• Research Organization: Department of Radiation Oncology, University of California, San Francisco, CA
• OSTI ID: 6702423
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 144:3; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
560152* -- Radiation Effects on Animals-- Animals
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DOGS
DOSES
ELECTROMAGNETIC RADIATION
IONIZING RADIATIONS
MAMMALS
NERVOUS SYSTEM
ORGANS
PATHOLOGY
RADIATION DOSES
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
TOMOGRAPHY
VERTEBRATES
X RADIATION