Antimutagenic properties of lactic acid-cultured milk on chemical and fecal mutagens

Journal Article · Mon Sep 01 00:00:00 EDT 1986 · J. Dairy Sci.; (United States)

DOI:https://doi.org/10.3168/jds.S0022-0302(86)80662-2· OSTI ID:6698486

Hosono, A; Kashina, T; Kada, T

The antimutagenic properties of milk cultured with Lactobacillus bulgaricus and Streptococcus thermophilus were examined using streptomycin-dependent strains of Salmonella in an in vitro assay system. The mutagens utilized for testing included 2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide, 4-nitroquinoline-N-oxide, and fecal mutagenic extracts from cats, monkeys, dogs and other mammals. Both types of cultured milk exhibited antimutagenic activity on all mutagens used. Antimutagenic activities of the cultured milks with 2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide and 4-nitroquinoline-N-oxide increased with incubation time but were thermolabile beyond 55/sup 0/C for 10 min.

• Research Organization: Shinshu Univ., Nagano-Ken, Japan
• OSTI ID: 6698486
• Journal Information: J. Dairy Sci.; (United States), Journal Name: J. Dairy Sci.; (United States) Vol. 69:9; ISSN JDSCA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
AZAARENES
AZINES
BACTERIA
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
CHEMICAL PROPERTIES
FECES
FOOD
HETEROCYCLIC COMPOUNDS
LACTOBACILLUS
MATERIALS
MICROORGANISMS
MILK
MUTAGEN SCREENING
MUTAGENS
NITRO COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PYRIDINES
QUINOLINES
SALMONELLA
SCREENING
STREPTOCOCCUS
WASTES