Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Influence of fraction size in radiotherapy on the late normal tissue reaction. II. Comparison of the effects of daily and twice-a-week fractionation on human skin

Journal Article · · Int. J. Radiat. Oncol., Biol. Phys.; (United States)
;
A comparison of the normal tissue reactions to daily and twice-a-week fractionation over 4 to 6 weeks was performed on postoperatively irradiated parasternal fields in patients with breast cancer. The radiation used was electron beams at 12-13 MeV. In this paper the authors present the degree of telangiectasia after 5 years. Generally, a more pronounced late reaction was found after twice-a-week fractionation than was predicted from the acute reaction. The findings imply that the cumulative radiation effect (CRE) formula has to be modified for both acute and late reactions in certain clinical situations. The main conclusion is that the isoeffect relationship varies significantly over the dose range used in clinical radiotherapy.
Research Organization:
Univ. of Goteborg, Sweden
OSTI ID:
6679230
Journal Information:
Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 10:5; ISSN IOBPD
Country of Publication:
United States
Language:
English

Similar Records

Influence of fraction size in radiotherapy on the late normal tissue reaction. I. Comparison of the effects of daily and once-a-week fractionation on human skin
Journal Article · Tue May 01 00:00:00 EDT 1984 · Int. J. Radiat. Oncol., Biol. Phys.; (United States) · OSTI ID:6980858
Influence of the overall treatment time in radiotherapy on the acute reaction: comparison of the effects of daily and twice-a-week fractionation on human skin
Journal Article · Tue May 01 00:00:00 EDT 1984 · Int. J. Radiat. Oncol., Biol. Phys.; (United States) · OSTI ID:6667744
Acute skin reactions in postoperative breast cancer patients receiving radiotherapy plus adjuvant chemotherapy
Journal Article · Sat Dec 31 23:00:00 EST 1977 · Am. J. Roentgenol.; (United States) · OSTI ID:6801307

Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BEAMS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
COMPARATIVE EVALUATIONS
CUMULATIVE RADIATION EFFECTS
DELAYED RADIATION EFFECTS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
ELECTRON BEAMS
ENERGY RANGE
ERYTHEMA
FRACTIONATED IRRADIATION
IRRADIATION
LEPTON BEAMS
MEDICINE
MEV RANGE
MEV RANGE 10-100
NUCLEAR MEDICINE
ORGANS
PARTICLE BEAMS
PATIENTS
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SKIN
SKIN DISEASES
SYMPTOMS
TELANGIECTASIS
THERAPY
VASCULAR DISEASES