Spirometry variability criteria--association with respiratory morbidity and mortality in a cohort of coal miners

Journal Article · Sun Mar 01 04:00:00 EST 1987 · Am. J. Epidemiol.; (United States)

OSTI ID:6671795

Kellie, S E; Attfield, M D; Hankinson, J L; Castellan, R M

To clarify the association between spirometry variability and respiratory morbidity and mortality, the authors analyzed data for miners examined in the first round of the National Coal Study, 1969-1971, and they compared groups of miners who failed with those who met each of two spirometry variability criteria: a 5% criterion recommended by the American Thoracic Society, and a 200 ml criterion used in prior research studies. Compared with miners who met the 5% criterion (the best two forced vital capacities must be within 5% or 100 ml of one another), the group that failed had a lower mean for forced expiratory volume in one second (FEV1), and odds ratios for cough, phlegm, wheeze, shortness of breath, and death of 1.75, 1.67, 1.76, 2.71, and 1.30, respectively. The findings for the 200 ml criterion (the best two FEV1s must be within 200 ml of one another) were somewhat different. The group that failed versus the group that met this criterion had a higher mean for FEV1, and odds ratios for cough, phlegm, wheeze, shortness of breath, and death of 1.13, 1.07, 1.15, 1.43, and 0.94, respectively. Although the findings differ for the two criteria, the findings demonstrate that increased spirometry variability is associated with poorer health.

• Research Organization: Univ. of Illinois College of Medicine, Chicago
• OSTI ID: 6671795
• Journal Information: Am. J. Epidemiol.; (United States), Journal Name: Am. J. Epidemiol.; (United States) Vol. 3; ISSN AJEPA
• Country of Publication: United States
• Language: English

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01 COAL, LIGNITE, AND PEAT
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BODY
COAL MINERS
COAL MINING
DISEASES
DYNAMIC FUNCTION STUDIES
EPIDEMIOLOGY
LUNGS
MINERS
MINING
MORTALITY
ORGANS
PERSONNEL
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
SYMPTOMS