Role of Tc-99m phosphate complexes and gallium-67 in the diagnosis and management of maxillofacial disease: concise communication

Journal Article · Thu Jan 01 04:00:00 EST 1981 · J. Nucl. Med.; (United States)

OSTI ID:6667755

Shafer, R B ^[1]; Marlette, J M; Browne, G A; Elson, M K

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1. Veterans Administration Medical Center, Minneapolis, MN

Osteomyelitis of maxillofacial bones is difficult to differentiate from the results of trauma or malignancy, yet successful management is dependent upon early diagnosis and appropriate therapy. To determine if gallium-67 could differentiate infection from trauma or malignancy, 61 Tc-99m phosphate scans and 52 gallium-67 scans were made in 42 patients with maxillofacial disease. In all patients, definitive diagnosis was determined by surgery and/or clinical followup. Bone scans were positive in 37 patients. Gallium-67 scans were positive in 16 patients. Subsequent surgery and/or clinical followup demonstrated active osteomyelitis in 15 patients. From the data we conclude that: (a) the addition of Ga-67 scanning to the bone scans in evaluation of maxillofacial disease contributes significantly to differentiating trauma from osteomyelitis; (b) radiographic changes do not accurately reflect bone activity or differentiate osteomyelitis from trauma or malignancy; and (c) reduction in accumulation of gallium-67 in followup scans is a useful indicator for the termination of therapy in osteomyelitis.

• OSTI ID: 6667755
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 22:1; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL LOCALIZATION
BODY
CARBOXYLIC ACID SALTS
CITRATES
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ESTERS
GALLIUM 67
GALLIUM ISOTOPES
HOURS LIVING RADIOISOTOPES
INJURIES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
OSTEOMYELITIS
PATIENTS
PHOSPHORIC ACID ESTERS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SKELETAL DISEASES
SKELETON
TECHNETIUM 99
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOISOTOPES