Crossed cerebellar diaschisis in ischemic stroke: a study of regional cerebral blood flow by /sup 133/Xe inhalation and single photon emission computerized tomography

Journal Article · Fri Jun 01 00:00:00 EDT 1984 · J. Cereb. Blood Flow Metab.; (United States)

DOI:https://doi.org/10.1038/jcbfm.1984.32· OSTI ID:6663016

Meneghetti, G; Vorstrup, S; Mickey, B; Lindewald, H; Lassen, N A

Seventy measurements of CBF were performed in 12 stroke patients by /sup 133/Xe inhalation and a rapidly rotating single photon emission computerized tomograph. CBF was measured every other day during the acute phase and at 2- and 6-month follow-up visits. A persistent contralateral cerebellar blood flow depression was evident in five patients with severe hemispheric low flow areas, which correlated with large, hypodense lesions on the computerized tomographic scan. In a sixth patient with a small, deep infarct, a transient crossed cerebellar low flow was observed, while the clinical symptoms persisted. It is concluded from this serial study that crossed cerebellar diaschisis is a common finding in completed stroke. It is probably caused by disconnection of the corticopontine pathways, a disconnection that tends to persist. The phenomenon is in fact less variable than the stroke-related CBF changes in the infarcted hemisphere, in which a period of relative hyperemia is frequently seen.

• Research Organization: Department of Neurology and Neuroradiology, University Hospital, Copenhagen, Denmark
• OSTI ID: 6663016
• Journal Information: J. Cereb. Blood Flow Metab.; (United States), Journal Name: J. Cereb. Blood Flow Metab.; (United States) Vol. 4:2; ISSN JCBMD
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BRAIN
CARDIOVASCULAR DISEASES
CENTRAL NERVOUS SYSTEM
CEREBRUM
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
INHALATION
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
NERVOUS SYSTEM
NUCLEI
ORGANS
PATIENTS
RADIOISOTOPES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
TOMOGRAPHY
TRACER TECHNIQUES
XENON 133
XENON ISOTOPES