Contralateral flow reduction in unilateral stroke: evidence for transhemispheric diaschisis
Using clinical presentation, angiography, computed tomography, and nuclear magnetic resonance imaging, 7 patients were identified who had strictly unilateral hemispheric infarction and unilateral cerebrovascular disease. In 6, cerebral blood flow measured by fluorine-18-fluoromethane inhalation and positron emission tomography was reduced in the contralateral hemisphere (p less than 0.05). Multiple regression analysis demonstrated a high correlation between contralateral flow reduction and the degree of flow impairment in the infarcted area (r = 0.941, p = 0.0014) but not with age, risk factor profile, blood pressure, PCO/sub 2/, hematocrit, or duration of stroke. We conclude that transhemispheric diaschisis best explains the contralateral flow reduction seen in supratentorial ischemic stroke.
- Research Organization:
- William S. Middleton Memorial Veterans Hospital, Madison, WI
- OSTI ID:
- 6075633
- Journal Information:
- Stroke; (United States), Journal Name: Stroke; (United States) Vol. 18:5; ISSN SJCCA
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOMEDICAL RADIOGRAPHY
BLOOD FLOW
BLOOD VESSELS
BODY
BRAIN
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
EMISSION COMPUTED TOMOGRAPHY
FLUORINE 18
FLUORINE ISOTOPES
HOURS LIVING RADIOISOTOPES
ISOTOPES
LIGHT NUCLEI
MAGNETIC RESONANCE
MATHEMATICS
MEDICINE
NERVOUS SYSTEM
NMR IMAGING
NUCLEAR MAGNETIC RESONANCE
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
POSITRON COMPUTED TOMOGRAPHY
RADIOISOTOPES
RADIOLOGY
REGRESSION ANALYSIS
RESONANCE
STATISTICS
TOMOGRAPHY
VASCULAR DISEASES