A toxological study of 3,6-BIS(3,5-Dimethyl-1-1-Pyrazolyl)1,2-Dihydro-1,2,4,5-Tetrazine
Technical Report
·
OSTI ID:6657861
The acute oral LD[sub 30/50] values for 3,6-BIS(3,5-Dimethyl-1-Pyrazolyl)-1,2-Dihydro-1,2,4,5-Tetrazine BIS(DMP)DHT are greater than 5g/kg. According to classical guidelines, the material would be considered only slightly toxic or practically nontoxic in both rats and mice. The sensitization study in the guinea pig did not show BIS(DMP)SHT to have potential sensitizing effects. Skin application studies on the rabbit demonstrated the material was cutaneously nonirritating. This material was also nonirritating in the rabbit eye application studies.
- Research Organization:
- Los Alamos National Lab., NM (United States)
- Sponsoring Organization:
- DOE; USDOE, Washington, DC (United States)
- DOE Contract Number:
- W-7405-ENG-36
- OSTI ID:
- 6657861
- Report Number(s):
- LA-12347-MS; ON: DE93009115
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEFENSE
450100 -- Military Technology
Weaponry
& National Defense-- Chemical Explosions & Explosives
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ANIMALS
AZINES
BODY
BODY AREAS
CHEMICAL EXPLOSIVES
EXPLOSIVES
EYES
FACE
HEAD
HETEROCYCLIC COMPOUNDS
MAMMALS
MICE
ORAL ADMINISTRATION
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
RABBITS
RATS
RODENTS
SENSE ORGANS
SKIN ABSORPTION
SORPTION
TOXICITY
UPTAKE
VERTEBRATES
450100 -- Military Technology
Weaponry
& National Defense-- Chemical Explosions & Explosives
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ANIMALS
AZINES
BODY
BODY AREAS
CHEMICAL EXPLOSIVES
EXPLOSIVES
EYES
FACE
HEAD
HETEROCYCLIC COMPOUNDS
MAMMALS
MICE
ORAL ADMINISTRATION
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
RABBITS
RATS
RODENTS
SENSE ORGANS
SKIN ABSORPTION
SORPTION
TOXICITY
UPTAKE
VERTEBRATES