A toxological study of 3,6-BIS(3,5-Dimethyl-1-1-Pyrazolyl)1,2-Dihydro-1,2,4,5-Tetrazine
Technical Report
·
OSTI ID:10135852
The acute oral LD{sub 30/50} values for 3,6-BIS(3,5-Dimethyl-1-Pyrazolyl)-1,2-Dihydro-1,2,4,5-Tetrazine BIS(DMP)DHT are greater than 5g/kg. According to classical guidelines, the material would be considered only slightly toxic or practically nontoxic in both rats and mice. The sensitization study in the guinea pig did not show BIS(DMP)SHT to have potential sensitizing effects. Skin application studies on the rabbit demonstrated the material was cutaneously nonirritating. This material was also nonirritating in the rabbit eye application studies.
- Research Organization:
- Los Alamos National Lab., NM (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- W-7405-ENG-36
- OSTI ID:
- 10135852
- Report Number(s):
- LA--12347-MS; ON: DE93009115
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEFENSE
450100
560300
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AZINES
CHEMICAL EXPLOSIONS AND EXPLOSIVES
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CHEMICALS METABOLISM AND TOXICOLOGY
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ORAL ADMINISTRATION
RABBITS
RATS
SKIN ABSORPTION
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450100
560300
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AZINES
CHEMICAL EXPLOSIONS AND EXPLOSIVES
CHEMICAL EXPLOSIVES
CHEMICALS METABOLISM AND TOXICOLOGY
EYES
MICE
ORAL ADMINISTRATION
RABBITS
RATS
SKIN ABSORPTION
TOXICITY