Postradiation ureteral obstruction: a reappraisal

Conference · Sun Feb 01 04:00:00 EST 1981 · Am. J. Obstet. Gynecol.; (United States)

OSTI ID:6643449

Muram, D; Oxorn, H; Curry, R H; Drouin, P; Walters, J H

Thirty-four patients who received radiation therapy for carcinoma of the cervix developed hydronephrosis. Twelve of 34 (35%) had no evidence of pelvic malignancy, and the obstruction was caused by periureteral fibrosis. The incidence of obstructive uropathy due to periureteral fibrosis not associated with recurrent tumor increased when the obstructing lesion was unilateral, the clinical staging of the cervical carcinoma prior to therapy was Stage IB or Stage II rather than Stage III or Stage IV, and the obstructing lesion appeared 2 or more years after the completion of radiation therapy. The appearance of hydronephrosis in association with ipsilateral leg edema, and sciatic pain in these patients strongly suggest a recurrent tumor. The diagnosis of periureteral fibrosis should be considered in all patients who develop obstruction of the urinary tract after radiation therapy for carcinoma of the cervix. Laparotomy is indicated if all other methods of investigation fail to confirm the presence of a malignant lesion.

• Research Organization: Univ. of Ottawa, Ontario
• OSTI ID: 6643449
• Conference Information: Journal Name: Am. J. Obstet. Gynecol.; (United States) Journal Volume: 139:3
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CARCINOMAS
COBALT 60
COBALT ISOTOPES
DELAYED RADIATION EFFECTS
DISEASES
EDEMA
EXTERNAL IRRADIATION
FEMALE GENITALS
INJURIES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEGS
LIMBS
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NERVES
NERVOUS SYSTEM
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION EFFECTS
RADIATION INJURIES
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SCIATIC NERVE
SIDE EFFECTS
SYMPTOMS
THERAPY
URETERS
URINARY TRACT
UROGENITAL SYSTEM DISEASES
UTERUS
YEARS LIVING RADIOISOTOPES