Dead time error with iodine-123 thyroid uptake measurements

Journal Article · Thu Sep 01 04:00:00 EDT 1988 · J. Nucl. Med. Technol.; (United States)

OSTI ID:6643388

Maguire, W J

Thyroid uptake measurements performed using iodine-123 (/sup 123/I) are subject to a systemic error due to dead time loss when the standard is derived based on a decay factor. Higher dead time loss with /sup 123/I is due to using more activity along with its better detection efficiency, higher count rate, and shorter half-life compared to that of /sup 131/I. The degree of error due to dead time loss may range from insignificant to extreme, depending on a number of factors. Degree of error is related to the activity administered, the window settings, the age and energy resolution of the instrumentation, and the elapsed time between standard and patient counts.

• Research Organization: Methodist Hospitals of Memphis, TN (USA)
• OSTI ID: 6643388
• Journal Information: J. Nucl. Med. Technol.; (United States), Journal Name: J. Nucl. Med. Technol.; (United States) Vol. 16:3; ISSN JNMTB
• Country of Publication: United States
• Language: English

Related Subjects

61 RADIATION PROTECTION AND DOSIMETRY
655003* -- Medical Physics-- Dosimetry
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DEAD TIME
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE GLANDS
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE 131
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
RADIONUCLIDE KINETICS
RADIOPHARMACEUTICALS
SENSITIVITY
THYROID
TIMING PROPERTIES
UPTAKE