Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Radiotherapy with thrice-a-day fractionation in a short overall time: clinical experiences

Journal Article · · Int. J. Radiat. Oncol., Biol. Phys.; (United States)
;
Forty-seven patients with head and neck cancer were treated with thrice-a-day fractionation (200 rad Co/sup 60/ three times per day, 5 days per week) to a total tumor dose of 4800 to 5400 rad over 9 to 11 days. Of this group, 22 advanced oral and pharyngo-laryngeal cancer patients had a 24-month follow-up. While early tolerance and skin reaction were quite acceptable, the rate of serious mucosal radionecrosis was high (55%) and 2-year survival was poor (14%). Less advantage was found over conventional fractionation; the probable causes, i.e., single dose size and irradiation volume dimension, are discussed.
Research Organization:
Unversita di Parma e Servizio di Radioterapia, Parma, Italy
OSTI ID:
6643384
Journal Information:
Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 7:1; ISSN IOBPD
Country of Publication:
United States
Language:
English

Similar Records

Preliminary results using twice-a-day fractionation in the radiotherapeutic management of advanced cancers of the head and neck
Journal Article · Wed Nov 30 23:00:00 EST 1977 · Am. J. Roentgenol.; (United States) · OSTI ID:5340116
Preliminary results using twice-a-day fractionation in the radiotherapeutic management of advanced cancers of the head and neck
Journal Article · Wed Nov 30 23:00:00 EST 1977 · Am. J. Roentgenol.; (United States) · OSTI ID:6630101
Short course high fractional dose irradiation in advanced and recurrent head and neck cancer
Conference · Mon Oct 01 00:00:00 EDT 1979 · Int. J. Radiat. Oncol., Biol. Phys.; (United States) · OSTI ID:5511763

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
COBALT 60
COBALT ISOTOPES
DIGESTIVE SYSTEM
DISEASES
DOSES
FRACTIONATED IRRADIATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IRRADIATION
IRRADIATION PROCEDURES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LARYNX
MEDICAL SURVEILLANCE
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORAL CAVITY
ORGANS
PATIENTS
PHARYNX
RADIATION DOSES
RADIATION EFFECTS
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOSENSITIVITY
RADIOTHERAPY
RESPIRATORY SYSTEM
SIDE EFFECTS
SKIN
SURVEILLANCE
SURVIVAL CURVES
THERAPY
YEARS LIVING RADIOISOTOPES