Mitotic index of megakaryocytes of mice after acute thrombocytopenia

Journal Article · Fri Dec 31 23:00:00 EST 1976 · Proc. Soc. Exp. Biol. Med.; (United States)

DOI:https://doi.org/10.3181/00379727-155-39762· OSTI ID:6641561

Odell, T T; Boran, D A

C3H mice were made severely thrombocytopenic by injection of antiplatelet serum. The peripheral platelet counts and the endomitotic index and number of marrow megakaryocytes were determined at intervals during the 6 days following treatment. Both the endomitotic index and the number of megakaryocytes increased and returned to pretreatment levels during that time, indicating a transitory stimulation of megakaryocytopoiesis in response to thrombocytopenia.

• Research Organization: Oak Ridge National Lab., TN
• OSTI ID: 6641561
• Journal Information: Proc. Soc. Exp. Biol. Med.; (United States), Journal Name: Proc. Soc. Exp. Biol. Med.; (United States) Vol. 155; ISSN PSEBA
• Country of Publication: United States
• Language: English

Related Subjects

550300* -- Cytology
59 BASIC BIOLOGICAL SCIENCES
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BLOOD FORMATION
BLOOD PLATELETS
BODY FLUIDS
BONE MARROW CELLS
CELL DIVISION
CONNECTIVE TISSUE CELLS
HISTOLOGY
INJECTION
INTAKE
INTRAPERITONEAL INJECTION
MAMMALS
MICE
MICROSCOPY
MITOSIS
ORGANIC COMPOUNDS
PROTEINS
RODENTS
SOMATIC CELLS
STIMULATION
THROMBOPOIESIS
VERTEBRATES