(Development of Bromine-77 from the LAMPF facility)
The objective of the work was to conduct the necessary studies required to evaluate the efficacy, potential benefit and role of bromine-77 labeled steroids in the detection and evaluation of treatment for hormone-dependent tumors. This report presents progress on the following tasks: An initial investigation concentrating on the radiobromination at carbon-6 or carbon-7 in selected simple steroids utilizing the nuclides, bromine-82 and bromine-77, analytical spectroscopy of radiolabeled compounds, and investigating the biodistribution, toxicology and tumor affinity of labeled agents.
- Research Organization:
- New Mexico Univ., Albuquerque, NM (USA). Dept. of Radiology
- Sponsoring Organization:
- DOE/ER
- DOE Contract Number:
- AS04-81EV10596
- OSTI ID:
- 6634477
- Report Number(s):
- DOE/EV/10596-T6; ON: DE91000117
- Country of Publication:
- United States
- Language:
- English
Similar Records
(Studies to evaluate the efficacy, potential benefit and role of Bromine-77 labeled steroids in the detection and evaluation of treatment for hormone-dependent tumors): Final report, March 1981--March 1984
Development of Bromine-77 from the LAMPF facility
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Sat Dec 31 23:00:00 EST 1988
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Development of Bromine-77 from the LAMPF facility
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OSTI ID:6545237
Related Subjects
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400703* -- Radiochemistry & Nuclear Chemistry-- Radioisotope Production
550201 -- Biochemistry-- Tracer Techniques
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
AFFINITY
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BROMINE 77
BROMINE 82
BROMINE ISOTOPES
CHEMICAL REACTIONS
CHROMATOGRAPHY
DAYS LIVING RADIOISOTOPES
DETECTION
DIFFRACTOMETERS
DISEASES
DOCUMENT TYPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ESTRADIOL
ESTRANES
ESTROGENS
HALOGENATION
HORMONES
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
ISOTOPES
LABELLED COMPOUNDS
LABELLING
LIQUID COLUMN CHROMATOGRAPHY
MEASURING INSTRUMENTS
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
PROGRESS REPORT
RADIATION DETECTORS
RADIOISOTOPES
RADIOLOGY
RADIOPHARMACEUTICALS
RADIOTHERAPY
SEPARATION PROCESSES
SPECTROSCOPY
STEROID HORMONES
STEROIDS
SYNTHESIS
THERAPY
X-RAY DIFFRACTOMETERS
400703* -- Radiochemistry & Nuclear Chemistry-- Radioisotope Production
550201 -- Biochemistry-- Tracer Techniques
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
AFFINITY
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BROMINE 77
BROMINE 82
BROMINE ISOTOPES
CHEMICAL REACTIONS
CHROMATOGRAPHY
DAYS LIVING RADIOISOTOPES
DETECTION
DIFFRACTOMETERS
DISEASES
DOCUMENT TYPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ESTRADIOL
ESTRANES
ESTROGENS
HALOGENATION
HORMONES
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
ISOTOPES
LABELLED COMPOUNDS
LABELLING
LIQUID COLUMN CHROMATOGRAPHY
MEASURING INSTRUMENTS
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
PROGRESS REPORT
RADIATION DETECTORS
RADIOISOTOPES
RADIOLOGY
RADIOPHARMACEUTICALS
RADIOTHERAPY
SEPARATION PROCESSES
SPECTROSCOPY
STEROID HORMONES
STEROIDS
SYNTHESIS
THERAPY
X-RAY DIFFRACTOMETERS