RPS2 of Arabidopsis thaliana: A leucine-rich repeat class of plant disease resistance genes

Journal Article · Fri Sep 23 04:00:00 EDT 1994 · Science (Washington, D.C.); (United States)

DOI:https://doi.org/10.1126/science.8091210· OSTI ID:6618629

Bent, A F; Kunkel, B N; Brown, K L; Staskawicz, B J ^[1]; Schmidt, R ^[2]; Giraudat, J; Leung, J ^[3]

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1. Univ. of California, Berkeley, CA (United States)
2. Cambridge Lab., Norwich (United Kingdom)
3. Institut des Sciences Vegetales, Gif-sur-Yvette (France)

Plant disease resistance genes function in highly specific pathogen recognition pathways. RPS2 is a resistance gene of Arabidposis thaliana that confers resistance against Pseudomonas syringae bacteria that express avirulence gene avrRpt2. RPS2 was isolated by the use of a positional cloning strategy. The derived amino acid sequence of RPS2 contains leucine-rich repeat, membrane-spanning, leucine zipper, and P loop domains. The function of the RPS2 gene product in defense signal transduction is postulated to involve nucleotide triphosphate binding and protein-protein interactions and may also involve the reception of an elicitor produced by the avirulent pathogen.

• OSTI ID: 6618629
• Journal Information: Science (Washington, D.C.); (United States), Journal Name: Science (Washington, D.C.); (United States) Vol. 265:5180; ISSN SCIEAS; ISSN 0036-8075
• Country of Publication: United States
• Language: English

Related Subjects

550400* -- Genetics
553003 -- Agriculture & Food Technology-- Pest & Disease Control-- (1987-)
59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES
AMINO ACID SEQUENCE
AMINO ACIDS
ARABIDOPSIS
CARBOXYLIC ACIDS
DISEASE RESISTANCE
GENES
LEUCINE
MAGNOLIOPHYTA
MAGNOLIOPSIDA
MOLECULAR STRUCTURE
ORGANIC ACIDS
ORGANIC COMPOUNDS
PLANTS