Interaction of electromagnetic fields with chondrocytes in gel culture. Final report, February-August 1989
The research accomplished during this project period focused on control experiments designed to establish whether cartilage cells from normal cartilage will continue to synthesize and accumulate normal extracellular matrix in agarose gel culture. This information is essential to properly design experiments to qualify changes in chondrocyte biosynthesis due to applied electromagnetic fields. The results suggest that both normal chondrocytes and swarm rat chondrosarcoma cells in agarose culture can continue to synthesize matrix macromolecules at a rate similar to or slightly higher than that in normal cartilage; also, that chondrocytes in agarose can successfully mediate assembly and accumulation of normal, mechanically functional extracellular matrix.
- Research Organization:
- Massachusetts Inst. of Tech., Cambridge, MA (USA). Dept. of Electrical Engineering and Computer Science
- OSTI ID:
- 6612422
- Report Number(s):
- AD-A-223397/1/XAB; CNN: F33615-87-D-0626
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BIOSYNTHESIS
BODY
CARTILAGE
CONNECTIVE TISSUE
DOCUMENT TYPES
ELECTROMAGNETIC FIELDS
MAMMALS
PROGRESS REPORT
RATS
RODENTS
SENSITIVITY
SYNTHESIS
TISSUE CULTURES
TISSUES
VERTEBRATES